바이오나노의약실험실
                 
 
 
 

Patents

[Issued (registered) Patents]



33.  (2015.02.05) Jon S, Kim S, Park S “Bipodal Peptide Binders”, Canada Patent 2741040.

32.  (2015.01.09) Jon S, Kim S, Kim D “BPB-based cargo delivery system”, Japan Patent 5677453.

31.  (2015.01.09) Jon S, Kim S, Kim D “Intracellular targeting bipodal peptide binder”, Japan Patent 5677454.

30.  (2014.09.17) Jon S, Kim S, Kim D “펩타이드의 타겟 친화도 개선방법”, Korea Patent 10-1443839.

29. (2014.03.14) Jon S, Lee IH “Nanoparticle-based Vaccine Delivery System Having Dual Function of Imaging and Delivery (이미징 및 운반 이중기능 나노입자-기반 백신 전달체)”, Korea Patent 10-1376675.

28. (2014.03.07) Jon S, Lee E, Lee J and Lee IH. “Transmucosal Delivery of Pharmaceutical Active Substances”, Japan Patent 5491485.

27. (2013.12.27) Jon S, Kim S, Saw PE, Lee SK, Kumar P “CD7-BPB Capable of Binding Specifically to CD7 (CD7 특이적으로 결합하는 CD7-BPB)”, Korea Patent 10-1347833.

26. (2013.10.24) Jon S, Jeon YS, Lee S, Lee M, Kim S “Methods for expression of target protein on vacuole surface and drug delivery system thereof (액포 표면에 목적단백질의 발현 방법 및 약물전달체)”, Korea Patent 10-1323847.

25. (2013.10.24) Jon S, Kim S “타겟 친화도가 유지되고 안정성이 개선된 D-앱타이드 ()”, Korea Patent 10-1323846.

24. (2013.10.24) Jon S, Kim S, Lee S, Gujrati V “Pharmaceutical Compositions for Treatment of Cancer Comprising Outer Membrane Vesicles as an Active Ingredient (외막소포체를 유효성분으로 포함하는 항암용 약제학적 조성물)”, Korea Patent 10-1323845.

23. (2013.10.18) Jon S, Kim S, Park S “Bipodal Peptide Binders”, Japan Patent 5390621.

22. (2013.02.14) Jon S, Kim S, Park S “Bipodal Peptide Binders”, Australian Patent 2009307249.

21. (2013.01.30) Jon S, Lee IH “Aptamer-based Targeted Chemoimmuno Therapy (앱타머 기반 표적지향 화학면역 요법)”, Korea Patent 10-1229811.

20. (2013.01.30) Jon S, Ko YT, Saw PE “Gene Delivery System (유전자 운반체)”, Korea Patent 10-1229809.

19. (2013.01.04) Jon S, Kim WB, Park S, Kim YS “Intracellular Delivery of Cargo Using Nanosyringe Array (나노주사기 어레이를 이용한 세포내 카르고 운반시스템)”, Korea Patent 10-1220989.

18. (2012.12.20) Jon S, Kim S, Park S  “바이포달 펩타이드 바인더(Bipodal Peptide Binder)”, Korea Patent 10-1216008.

17. (2012.05.24) Jon S, Kim S, Jeon WS, Kim D, Kim D  “칼슘 이온 검출용 센서(calcium ion sensor)”, Korea Patent 10-1151800.

16. (2012.05.24) Jon S, Kim S, Park S “바이포달 펩타이드 바인더(Bipodal Peptide Binder)”, Korea Patent 10-1151805.

15. (2010.02.02) Jon S, Park S, Sung D, Yang H “다기능성 고분자막 및 그의 용도”, Korea Patent 10-1050690.

14. (2010.02.02) Jon S, Choi IS, Park S, Cho WK “수 반발성 랜덤 공중합체 및 이 공중합체로 코팅된기판”, Korea Patent 10-0941464.

13. (2009.06.23) Farokhzad O, Jon S, Langer R* “Controlled release polymer nanoparticle containing bound nucleic acid ligand for targeting”, US Patent 7,550,441.

12. (2008.06.17) Kim K, Jon S, Selvapalam N and Oh DH “Hydroxycucurbituril derivatives, their preparation methods and uses”, US Patent 7388099.

11. (2008.05.07) Jon S, Kim D, Jeong YY and Kim JI “Gold Nanoparticle-Containing CT Contrast Agent (금 나노입자를 포함하는 CT 조영제”, Korea Patent 0827293.

10. (2008.04.28) Jon S, Jeong YY, Lee H, Kim JI, Lee E, Jang NK and Kim D “Nanoparticles Coated with Silicon-Containing Polymers and Their Use as Contrast Agents(실리콘 포함 수용성 고분자로 코팅된 나노입자 및 그의 조영제로서의 용도)”, Korea Patent 0827292.

9. (2007.12.27) Jon S and Lee E “항암제의 경점막 운반시스템(Transmucosal Delivery System for Anticancer Agents)”, Korea Patent 0791414.

8. (2007.10.08) Jon S and Lee E “단백질 또는 펩타이드의 경점막 운반시스템(Transmucosal Delivery System for Proteins or Peptides)”, Korea Patent 0766820.

7. (2006.03.28) Kim K, Jeon WS, Kim D, Oh DH and Jon S. “Ultrathin film using cucurbituril derivatives, and process for the preparation thereof”, Korea Patent 0567347.

6. (2006.02.15) Kim K, Jon S, Jeon YJ, Oh DH and Narayanan S. “Nanoparticles comprising cucurbituril derivatives, pharmaceutical composition containing the same, and process for the preparation thereof”, Korea Patent 0554156.

5. (2006.01.17) Kim K, Kang J, Jeon WS, Jon S, Narayanan S and Oh DH. “Solid substrate bonded with cucurbituril derivatives and biochip using the same”, Korea Patent 0545583.

4. (2005.11.09) Kim K, Balagilen G, Oh DH, Koh YH and Jon S. “Silica gel bonded with cucurbiturils”, Korea Patent 0528959.

3. (2005.06.24) Kim K, Jon S, Narayanan S and Oh DH. “Hydroxy cucurbiturils and their derivatives, their preparation methods and uses”, Korea Patent 0499275.

2. (2003.04.17) Kim K, Jon S, Kim JH, Kim MK, Jeon WS and Park SH. “1,3,5-tris(substituted-catecholylmethyl)-2,4,6-trialkylbenzene macrobicycles and their use for ion sensors”, Korea Patent 0382365.

1. (2002.05.07) Kim K*, Chin J*, Oh J, Jon S et. al. “1,3,5-tris(substituted heterocycle-1-ylmethyl)-2,4,6-tris substituted cyclic compounds, a chemical sensor composition and a chemical sensor using the same”, Korea Patent 0337386.



[Pending (filed) Patents]


34. (2014.08.01) 임성갑,전상용,최민석,이학래. “세포배양 기판, 이의 제조방법 및 용도”, Korea Patent 10-2014-0099059.

33. (2014.04.11) 전상용,전형수,김대진. “환형의 베타-헤어핀 기반 펩타이드 바인더 및 이의 제조방법”, Korea Patent 10-2014-0043633.

32. (2013.12.27) 전상용,이용현. “빌리루빈으로 구성된 나노입자 및 이를 이용한 용도”, Korea Patent 10-2013-0165718.

31. (2013.12.24) 전상용,김성현. “VEGF에 특이적으로 결합하는 VEGF-BPB”, Korea Patent 10-2013-0162797.

30. (2012.07.27) 전상용,김성현. “Methods for Improving Target Affinity of Peptides (펩타이드의 타겟 친화도 개선 방법”, Korea Patent 10-2012-0082696.

29. (2011.12.29) 전상용,김성현,페어어 쏘. “CD7-BPB Capable of Binding Specifically to CD7 (CD7 특이적으로 결합하는 CD7-BPB”, Korea Patent 10-2011-0145658.

28. (2011.05.17) 전상용,전영수,이상은,이미리암,김성현. "Methods for expression of target protein on vacuole surface and drug delivery system thereof(액포 표면에 목적단백질의 발현 방법 및 약물전달체)", Korea Patent 10-2011-0046458.

27. (2011.04.19) 전상용,이인현. "Nanoparticle-based Vaccine Delivery System Having Dual Function of Imaging and Delivery (이미징 및 운반 이중기능 나노입자-기반 백신 전달체)", Korea Patent 10-2011-0036017

26. (2011.04.08) 전상용, 김성현. “타겟 친화도가 유지되고 안정성이 개선된 d-앱타이드 및 레트로 인버소 앱타이드”, Korea Patent 10-2011-?.

25. (2011.01.31) 전상용,성대경,최민석. "자성입자를 이용한 label free 박테리아 바이오센서 개발", Korea Patent 10-2011-0009391.

24. (2011.01.21) 전상용,김성현,이상은, 비플 부리지모한 구자라티. "Phamaceutical Compositions for Treatment of Cancer Comprising Outer Membrane Vesicles as Active Ingredient  (외막소포체를 유효성분으로 포함하는 항암용 약제학적 조성물)", Korea Patent 10-2011-0006211.

23. (2010.12.17) 전상용,김성현,박세호. "Bipodal Peptide Binder (바이포달 펩타이드 바인더)", US12/999,717.

22. (2010.12.16) 전상용,김성현,박세호. "Bipodal Peptide Binder (바이포달 펩타이드 바인더)", EP 09822 191.4.

21. (2010.12.03) 전상용,김성현,김대진. "세포내 타겟 결합용 바이포달 펩타이드 바인더",PCT/KR2010/008646.

20. (2010.12.03) 전상용,김성현,박세호,김동규,박진호,쏘우페이어. "BPB-기반 카르고 운반 시스템",PCT/KR2010/008645.

19. (2010.05.20) 전상용,이인현. “Aptamer-based Targeted Chemoimmuno Therapy (앱타머 기반 표적지향 화학면역 요법)”, Korea Patent 10-2010-0047567.

18. (2010.04.20) 전상용,김성현,박세호,김대진,이상헌. “RTK-BPB Capable of Binding Specifically to RTK (RTK에 특이적으로 결합하는 RTK-BPB)”, Korea Patent 10-2010-0036608.

17. (2010.04.20) 전상용,김성현,박세호,김대진,이상헌. “GPCR-BPB Capable of Binding Specifically to GPCR (GPCR에 특이적으로 결합하는 GPCR-BPB)”, Korea Patent 10-2010-0036599.

16. (2010.04.20) 전상용,김성현,박세호,김대진,이상헌. “TF-BPB Capable of Binding Specifically to Transcription Factors (전사인자에 특이적으로 결합하는 전사인자-BPB)”, Korea Patent 10-2010-0036601.

15. (2010.04.20) 전상용,김성현,박세호,김대진,이상헌. “Ion Channel-BPB Capable of Binding Specifically to Ion Channel (이온채널에 특이적으로 결합하는 이온채널-BPB)”, Korea Patent 10-2010-0036618.

14. (2010.04.20) 전상용,김성현,박세호,김대진,이상헌. “Cytokine-BPB Capable of Binding Specifically to Cytokine (Cytokine에 특이적으로 결합하는 cytokine-BPB)”, Korea Patent 10-2010-0036607.

13. (2010.04.14) 전상용,고영탁, 써 페이에르. “Gene Delivery System (유전자 운반체)”, Korea Patent 10-2010-0034361.

12. (2009.12.11) 전상용,김성현. “Bipodal Peptide Binders for Intracelluar Targets and Their Construction Methods (세포내 타겟 결합용 바이포달 펩타이드 바인더)”, Korea Patent 10-2009-0123134.

11. (2009.12.11) 전상용,김성현. “Bipodal Peptide Binders-Based Cargo Delivery System (BPB-기반 카르고 운반시스템)”, Korea Patent 10-2009-0123237.

10. (2009.02.04) 전상용,김성현,박정원,김동규,김대진. “칼슘이온 검출용 센서(Sensors for Detecting Calcium Ions”, Korea Patent 10-2009-0068028-63.

9. (2008.10.20) 전상용,김성현. “바이포달 펩타이드 바인드(Bipodal Peptide Binders)”, Korea Patent 10-2008-0102648; (2009.10.20) 전상용,김성현,박세호. 우선권주장 KR 10-2009-0099981; (2009.10.20) PCT/KR2009/006059.

8. (2008.10.15) 전상용,김원배,박상진,김연수 “Intracellular Delivery of Cargo Using Nanosyringe Array (나노주사기 어레이를 이용한 세포내 카르고 운반)”, Korea Patent 10-2008-0101316; (2009.10.14) 우선권주장 KR 10-2009-0097952.

7. (2008.03.04) 전상용,최인성,박상진,조우경 “A Novel Random Copolymer for Water-Repellent Coating and Substrate Coated with the Same (수반발성 코팅용 랜덤 공중합체 및 이 공중합체로 코팅된 기판)”, Korea Patent 10-2008-0020243. (2009.03.02) 국제출원 PCT/KR2008/005196.

6. (2007.09.07) 전상용,박상진,성대경,양해식 “Multi-Functional Polymeric Layers and Its Uses”, Korea Patent 10-2007-0090742. (2008.09.03) PCT/KR2008/005170.

5. (2007.09.06) 전상용,유미경 “Multi-Functional Complex for Imaging and Drug Delivery”, Korea Patent 10-2007-0090628.

4. (2007.08.29) Jon S, Lee E, Lee J and Lee IH. “Transmucosal Delivery of Pharmaceutical Active Substances”, U.S. Patent (CIP) 11/847,237.

3. (2007.08.03) Jon S, Jeong YY, Lee H, Yu MK, Park S and Kim JI. “Thermally Crosslinked Contrast Agents”, U.S. Patent 11/833,873.

2. (2007.05.17) Farokhzad OC, Jon S, Bagalkot V, Zhang L, Teply B, Levy-Nissenbaum E, Langer R. “Aptamer-Directed Drug Delivery”, PCT/US07/69144.

1. (2006.10.26) Jon S, Khademhosseini A, Langer R, Suh KY. “Patterned surfaces and polymeric microstructures within robust microfluidic channels”, US Patent 20060237080 (A1).



Books


2. Bagolkot V, Yu M and Jon S* “Nanoparticles for Combined Cancer Imaging and Therapy”, Edited by Xiaoyuan Chen Nanotechnology-Based Molecular Imaging (Publisher: John Wiley & Sons), December 2010, ISBN 978-04-705-2115-1.

1. Farokhzad O, Jon S, Langer R* “Nanotechnology for Cancer Therapy”, Taylor & Francis Group, LLC., December 2006.



Invited Lecture (International Conference)


1. “Multifunctional Nanoparticles for Cancer Imaging and Therapy” 18th EORTC-AACR-NCI Conference, Prague in Czech, Nov 6-10, 2006.

2. “Drug-loaded superparamagnetic nanoparticles for combined cancer imaging and therapy” The 5th A3 (China-Japan-Korea) Foresight Meeting on Gene Therapy, Jun 11-13, 2008, Pohang in Korea.

3. “Conjugated Chitosan as a Novel Platform for Oral Delivery of Anticancer Drugs”, The 7th KCIST International Conference on ‘Progress on Innovative Drug Delivery’, Aug 24-26, 2008, Jeju Island in Korea.

4. “Multifunctional nanoparticles for combined cancer imaging and therapy” Nano Korea 2008, Aug 27-29, 2008.

5. “Translational research of superparamagnetic iron oxide nanoparticles in cancer MRI” 12th Asian Oceanian Congress of Radiology, Oct 24-28, 2008, Seoul in Korea.

6. “Aptamer-mediated targeted drug delivery to cancer” 9th International Congress on Cell Biology , Oct 7-10, 2008, Seoul in Korea.

7. “Multifunctional Superparamagnetic Iron Oxide Nanoparticles for Combined Cancer Imaging and Therapy” 5th International Conference on Materials for Advanced Technology (ICMAT 2009), Jun 28 - Jul 3, 2009 in Singapore.

8. “Multifunctional Magnetic Nanoparticles for Combined Cancer Imaging and Therapy” 42nd IUPAC Congress, Aug 2-7, 2009, Glasgow in United Kingdom.

9. “Novel Nano-tweezers Peptides as Potential Biotherapeutics”, 2nd International Conference on Antibodies, Mar 24-26, 2010, Beijing, China.

10. “Aptamer-Mediated Drug Delivery for Prostate Cancer Therapy”, Particles 2010, May 22-25, 2010, Florida, USA.

11. “Combined Cancer Imaging and Therapy Using Nano Contrast Agents”, 20th International Seoul Radiology Symposium, Oct 2, 2010 in Seoul, Korea.

12. “Prostate Cancer Imaging and Therapy Using Aptamer-Nanoparticle Conjugates”, 1st P-NanoSeoul Forum, Oct 13, 2010 in Seoul, Korea.

13. “Cancer Imaging and Therapy Using Aptamer-conjugated Nano-vehicles”, 2011 Seoul National University Cancer Research Institute International Symposium, Apr 15, 2011 in Seoul, Korea.

14. “Bio-inspired Design and Potential Biopharmaceutical Applications of Novel Peptide Aptamer (Aptide)”, 6th International Conference on Materials for Advanced Technology (ICMAT 2011), Jun 27 - Jul 2, 2011 in Singapore.

15. “Bio-inspired Design and Biopharmaceutical Applications of Novel Peptide Aptamers (Aptides)”3rd Symposium of Utah-Inha Drug Delivery System, Jun 10, 2011 in Incheon, Korea.

16. “Aptide-based Nanomedicine for Cancer Imaging and Therapy”, Recent Advances in Nanomedicine & Molecular Imaging, Aug 24, 2011 in Ilsan, Korea.

17. “Bio-inspired Design and Potential Biopharmaceutical Applications of Novel Peptide Aptamers (Aptides)”, 3rd Asia Biomaterials Conference (ABMC), Sep 15-17, 2011 in Busan, Korea.

18. “Aptide-based Nanomedicine”, 5th International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2011), Nov 9-12, 2011 in Jeju Island, Korea.

19. “Aptide & Aptide-based Biomedical Applications”, 3rd International Conference on NAPA 2012, Mar 15-17, 2012 in Seoul, Korea.

20. "Bio-inspired Design and Potential Biomedical Applications of Aptides", 2012 CRI Cancer Symposium, May 16-19, 2012 in Seoul, Korea.

21. “Aptide & Aptide-based Biomedical Applications”, 15th International Biotechnology Symoposium and Exhibition (IBS 2012), Sep 16-21, 2012 in Daegu, Korea.

22. “Bio-inspired Design and Potential Biomedical Applications of Aptides”, 2012 International Conference of the Korean Society of Pharmaceutical Sciences and Technology, Nov 29-30, 2012 in Gwangju, Korea.

23. “Aptide-mediated Targeted Cancer Imaging and Therapy”, International Advanced Drug Delivery Symposium (IADDS 2013), May 02-03, 2013 in Hsinchu, Taiwan.

24.  “Biomedical Applications of a Novel Class of High-affinity Peptides (Aptides)”, US-Korea Conference on Science, Technology, and Entrepreneurship (UKC 2013), Aug 07-11, 2013 in New York, USA.

25.  “Biomedical Applications of a Novel Class of High-affinity Peptides (Aptides)”, Bio Korea 2013, Sep 13, 2013 in Ilsan, Korea.

26. “Multi-stimuli-responsive nanovesicles for anti-inflammation and anti-cancer therapy”, 3rd Global Congress on Nanoengineering for Medicine and Biology (ASME 2014), Feb 2-5, 2014 in San Francisco, USA.

27. “Biomedical Applications of a Novel Class of High-affinity Peptides (Aptides)”, 94th Annual Meeting of the Chemical Society of Japan, March 27-30, 2014, Nagoya, Japan.

28. “Biomedical Applications of Aptides”, The 4th Asia Pacific Protein Association (APPA2014), May 17-20, 2014, Jeju Island, Korea.

29. “Light/ROS-responsive nanovesicles for anticancer and anti-inflammation therapy”, The 1st International Conference & Exhibition for Nanopia 2014, Nov 11-13, 2014, Changwon, Korea.

30. “Light/ROS-responsive nanovesicles for anticancer and anti-inflammation therapy”, 2nd IBN International Symposium, Dec 8-9, 2014, Singapore.

31. “Biomedical Applications of a Novel Class of High-affinity Peptides (Aptides)”, 3rd Asian Chemical Biology Conference, Dec 15-17, 2014, Singapore.

32. “Multi-stimuli-responsive nanovesicles for anti-cancer and anti-inflammation therapy”, Cutting Edge Discovery in Chemical Biology for future Biomedical Sciences, Dec 18, 2014, NTU, Singapore.

33. “Multi-stimuli-responsive nanovesicles for anti-inflammation and anti-cancer therapy”, The 5th Asian Biomaterials Congress, May 6-9, 2015, Taipei, Taiwan.

34. “Multi-stimuli-responsive nanovesicles for anti-inflammation and anti-cancer therapy”, The European Summit for Clinical Nanomedicine and Targeted Medicine, Jun 28-Jul 1, 2015, Basel, Swiss.

35. “A Nanomedicinal Arsenal for Cancer Imaging and Therapy”, 4th Nano Today Conference, Dec 6-10, 2015, Dubai, UAE.

36. “Multi-stimuli-responsive nanovesicles for anti-inflammation and anti-cancer therapy”, The European Summit for Clinical Nanomedicine and Targeted Medicine, Dec 15-20, 2015, Hawaii, USA.


Other Activities


1. In 2006, “Controlled release polymer nanoparticle containing bound nucleic acid ligand for targeting” was licensed to BIND Biosciences, Inc (Cambridge, MA).

2. In 2007, “Oral Anticancer Drug Delivery” was licensed to AnyGen Corp (Gwangju, Korea).

3. In 2007, “Oral Insulin Delivery” was licensed to AnyGen Corp (Gwangju, Korea).

4. In 2007, “Cancer Imaging Using TCL-SPION” was licensed to AnyGen Corp (Gwangju, Korea).

5. In 2008, “Aptamer-Mediated Targeted Drug Delivery” was licensed to BIND Biosciences, Inc (Cambridge, MA) and Selecta Biosciences, Inc (Watertown, MA).

6. In 2011, “Bipodal Peptide Binders” was licensed to Aptide, Inc. (Gwangju, Korea).

7. In 2011, “Bioadhesive Polymers-Coated Controlled Release Polymer Particles as Efficient Oral Delivery Vehicles for Bipharmaceuticals” was licensed to BIND Biosciences, Inc (Cambridge, MA) and Selecta Biosciences, Inc (Watertown, MA).